You can modify the library on the
sqlite3_open_v2 function to detect the file name being requested to be opened and then changing it.
Or you can rename libsqlite3.so to a specific name to be used only by this app, change the app to use this new lib, and modify that function to just use a fixed URI string.
Please also make sure you have license to make this. As you are modifying an underlying library and not the application itself, maybe this can be allowed.
You will also need a LiteSync license for this.